Intralesional cryosurgery enhances the involution of recalcitrant auricular keloids: a new clinical approach supported by experimental studies

To explain the mechanism of action of a novel intralesional cryoprobe, thermal
behavior measurements, and histological studies were performed in swine muscle
specimens after intralesional cryosurgery ex vivo. Efficacy and safety of the intralesional cryoprobe was further assessed in ten recalcitrant auricular keloids in
nine Caucasian patients.